BDBM427320 (S)-2,4-dimethyl-1-(2-methyl-4-(2-(trifluoromethyl)pyrimidin-4-yl)phenoxy)pentan-2-amine::US10544120, Example 330

SMILES CC(C)C[C@@](C)(COc1ccc(cc1C)-c1ccnc(n1)C(F)(F)F)NC(=O)OC(C)(C)C

InChI Key InChIKey=JBSIDAOHQJUDKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427320   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427320(US10544120, Example 330 | (S)-2,4-dimethyl-1-(2-me...)
Affinity DataIC50: 7.30nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent