BDBM427321 (S)-1-(2-fluoro-4-(2-(trifluoromethyl)pyrimidin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine::US10544120, Example 331

SMILES CC(C)C[C@](C)(N)COc1ccc(cc1F)-c1ccnc(n1)C(F)(F)F

InChI Key InChIKey=RXFKHOFNIOSORD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427321   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427321(US10544120, Example 331 | (S)-1-(2-fluoro-4-(2-(tr...)
Affinity DataIC50: 45nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent