BDBM429947 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-[(2-oxo-2-pyrrolidin- 1-ylethyl)sulfanyl]-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 136

SMILES Fc1ccc(NC(=N)c2nonc2SCC(=O)N2CCCC2)cc1Br

InChI Key InChIKey=KHVOGFIIKGFATL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429947   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429947(US10538497, Example 136 | N-(3-bromo-4-fluoropheny...)
Affinity DataIC50: 112nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent