BDBM430042 US10538528, Compound 24

SMILES CC1C(=O)Nc2ncnc(N3CCC(CC3)c3nc(ccc3NCCN3CCCC3)-c3nccs3)c12

InChI Key InChIKey=VANVVQOKOBHKMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430042   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430042(US10538528, Compound 24)
Affinity DataIC50:  0.600nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430042(US10538528, Compound 24)
Affinity DataIC50:  1.90nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent