BDBM430074 US10538528, Compound B

SMILES CC(C)(C)NCCn1cc(nc1C1CCN(CC1)c1ncnc2NC(=O)C(C)(C)c12)-c1cncc(F)c1

InChI Key InChIKey=OOEGPNVMAUPTKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430074   

TargetRibosomal protein S6 kinase alpha-1(Human)
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430074(US10538528, Compound B)
Affinity DataIC50: 657nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent