BDBM4302 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]prop-2-enamide::Tyrphostin deriv. 44::cid_5328772
SMILES C[C@@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1
InChI Key InChIKey=UMGQVUWXNOJOSJ-KMHUVPDISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4302
Affinity DataIC50: 400nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Tennessee Health Sciences Center
Curated by ChEMBL
University Of Tennessee Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.00E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair