BDBM4303 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)acrylamide::(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide::(E)-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-N-(3-phenylpropyl)prop-2-enamide::CHEMBL53898::MLS000069704::SMR000058519::TYRPHOSTIN AG 555::Tyrphostin deriv. 46::cid_5328770

SMILES: Oc1ccc(\C=C(/C#N)C(=O)NCCCc2ccccc2)cc1O

InChI Key: InChIKey=GSQOBTOAOGXIFL-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 4303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein HSP 90-alpha (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	7.4	23
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Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Steroidogenic factor 1 (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2C (Rat)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2B (Rat)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2A (Rat)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4303 (MLS000069704 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
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