BDBM4304 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide::CHEMBL56731::cid_5328771::tyrphostin 1

SMILES: Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O

InChI Key: InChIKey=HKHOVJYOELRGMV-UHFFFAOYSA-N

Data: 13 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 4304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
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Platelet-derived growth factor receptor beta (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Large T antigen (SV40)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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26S proteasome non-ATPase regulatory subunit 14 (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Bovine)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2C (Rat)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2B (Rat)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2A (Rat)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4304 (cid_5328771 | CHEMBL56731 | (2E)-2-cyano-3-(3,4-di...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
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