BDBM4308 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide::CHEMBL440298::Tyrphostin deriv. 56

SMILES: Oc1ccc(\C=C(/C#N)C(=O)NCCCCc2ccccc2)cc1O

InChI Key: InChIKey=GWCNJMUSWLTSCW-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 4308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2A (Rat)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2C (Rat)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rat)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4308 (CHEMBL440298 | (2E)-2-cyano-3-(3,4-dihydroxyphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair