BDBM4313 (2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide::AG 490::AG-490::CHEMBL56543::Tyrphostin AG 490::Tyrphostin B42::Tyrphostin deriv. 42

SMILES: Oc1ccc(\C=C(/C#N)C(=O)NCc2ccccc2)cc1O

InChI Key: InChIKey=TUCIOBMMDDOEMM-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 4313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2B (Rat)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2C (Rat)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1/2A (Rat)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosyl-DNA phosphodiesterase 1 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM4313 (CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair