BDBM4314 (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 66::cid_1838043

SMILES: Oc1ccc(\C=C(/C#N)C(=O)N2CCc3ccccc23)cc1O

InChI Key: InChIKey=MYKCTDWWIWGLHW-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 4314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4314 (cid_1838043 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcar...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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26S proteasome non-ATPase regulatory subunit 14 (Human)	BDBM4314 (cid_1838043 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcar...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	798	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Bovine)	BDBM4314 (cid_1838043 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcar...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4314 (cid_1838043 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcar...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4314 (cid_1838043 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcar...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair