BDBM4317 2-[(4-methoxyphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 1

SMILES [#6]-[#8]-c1ccc(\[#6]=[#6](\C#N)C#N)cc1

InChI Key InChIKey=UOHFCPXBKJPCAD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4317   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4317(2-[(4-methoxyphenyl)methylidene]propanedinitrile |...)
Affinity DataKi: >4.00E+5nM ΔG°: >-4.59kcal/mole IC50: >1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
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