BDBM432484 N-(1-((2-aminoethyl)sulfonyl)piperidin-4- yl)-5-cyclopropylisoxazole-3-carboxamide::US10577363, Compound 183

SMILES: c1c(onc1C(=O)NC2CCN(CC2)S(=O)(=O)CCN)C3CC3

InChI Key: InChIKey=AMCHZZBLDUVCGF-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM432484 (N-(1-((2-aminoethyl)sulfonyl)piperidin-4- yl)-5-cy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM432484 (N-(1-((2-aminoethyl)sulfonyl)piperidin-4- yl)-5-cy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair