BDBM4346 (2E)-2-cyano-3-(4-methylphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 30

SMILES Cc1ccc(\C=C(/C#N)C(O)=O)cc1

InChI Key InChIKey=VSMAAVBAABUVMQ-UXBLZVDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4346   

TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Medical School Duluth

Curated by ChEMBL
LigandPNGBDBM4346((2E)-2-cyano-3-(4-methylphenyl)prop-2-enoic acid |...)
Affinity DataIC50:  500nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4346((2E)-2-cyano-3-(4-methylphenyl)prop-2-enoic acid |...)
Affinity DataIC50:  1.35E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed