BDBM4363 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide::AG 213::CHEMBL77030::RG-50864::T7540 (Tyrphostin 47)::Tyrphostin A47::alpha-Cyano-(3,4-dihydroxy)thiocinnamide::benzylidenemalononitrile (BMN) deriv. 47

SMILES: NC(=S)C(=C\c1ccc(O)c(O)c1)\C#N

InChI Key: InChIKey=ZGHQGWOETPXKLY-UHFFFAOYSA-N

Data: 1 KI  14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 4363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor [538-972] ()	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.5	22
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Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.5	22
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Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.5	22
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Protein-glutamine gamma-glutamyltransferase 2/Receptor protein-tyrosine kinase (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	37
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Dynamin-1 (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosyl-DNA phosphodiesterase 1 (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4363 (alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem		850	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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