BDBM436742 6-(3,4-Difluorophenyl)-3-methyl-1-[(5-methyl-1,3,4-oxadiazol-2- yl)methyl]imidazo[4,5-b]pyridin-2-one::US10617676, Example 73::US11207298, Example 73

SMILES Cc1nnc(Cn2c3cc(cnc3n(C)c2=O)-c2ccc(F)c(F)c2)o1

InChI Key InChIKey=MPRKHIZLBGLDHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436742   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436742(US10617676, Example 73 | 6-(3,4-Difluorophenyl)-3-...)
Affinity DataIC50: 314nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436742(US10617676, Example 73 | 6-(3,4-Difluorophenyl)-3-...)
Affinity DataIC50: 314nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent