BDBM436886 1-[(4-Fluoro-3-methyl-phenyl)methyl]-6-[3-(trifluoromethyl)phenyl]-3H- imidazo[4,5-b]pyridin-2-one::US10617676, Example 221::US11207298, Example 221

SMILES Cc1cc(Cn2c3cc(cnc3[nH]c2=O)-c2cccc(c2)C(F)(F)F)ccc1F

InChI Key InChIKey=BUUIFURXARJXQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436886   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436886(US10617676, Example 221 | 1-[(4-Fluoro-3-methyl-ph...)
Affinity DataIC50: 8.71E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436886(US10617676, Example 221 | 1-[(4-Fluoro-3-methyl-ph...)
Affinity DataIC50: 8.71E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent