BDBM436929 (R/S)-1-(Azetidin-2-ylmethyl)-6-[2-fluoro-3-(trifluoromethyl)phenyl]-3H- imidazo[4,5-b]pyridin-2-one::US10617676, Example 264::US11207298, Example 264

SMILES Fc1c(cccc1C(F)(F)F)-c1cnc2[nH]c(=O)n(CC3CCN3)c2c1

InChI Key InChIKey=VKQKBJFYHCDWAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436929   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436929(US10617676, Example 264 | (R/S)-1-(Azetidin-2-ylme...)
Affinity DataIC50: 44nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436929(US10617676, Example 264 | (R/S)-1-(Azetidin-2-ylme...)
Affinity DataIC50: 44nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent