BDBM436941 6-(3-Fluorophenyl)-1-[(4-methyl-3-pyridyl)methyl]-3H-imidazo[4,5-b]pyridin- 2-one::US10617676, Example 276::US11207298, Example 276

SMILES Cc1ccncc1Cn1c2cc(cnc2[nH]c1=O)-c1cccc(F)c1

InChI Key InChIKey=POKYDAYYHJBBKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436941   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436941(US10617676, Example 276 | 6-(3-Fluorophenyl)-1-[(4...)
Affinity DataIC50: 34nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436941(US10617676, Example 276 | 6-(3-Fluorophenyl)-1-[(4...)
Affinity DataIC50: 34nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent