BDBM436971 6-(4-Chloro-3-methyl-phenyl)-1-[(5-fluoro-3-pyridyl)methyl]-3H-imidazo[4,5- b]pyridin-2-one::US10617676, Example 306::US11207298, Example 306

SMILES Cc1cc(ccc1Cl)-c1cnc2[nH]c(=O)n(Cc3cncc(F)c3)c2c1

InChI Key InChIKey=ZWPLTMJMBILTQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436971   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436971(US10617676, Example 306 | 6-(4-Chloro-3-methyl-phe...)
Affinity DataIC50: 86nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436971(US10617676, Example 306 | 6-(4-Chloro-3-methyl-phe...)
Affinity DataIC50: 86nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent