BDBM436988 1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[5-(trifluoromethyl)-2-thienyl]-3H- imidazo[4,5-b]pyridin-2-one::US10617676, Example 323::US11207298, Example 323

SMILES FC(F)(F)c1ccc(s1)-c1cnc2[nH]c(=O)n(CC(=O)N3CCC3)c2c1

InChI Key InChIKey=INTCEBHIEDIHMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436988   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436988(US10617676, Example 323 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 41nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436988(US10617676, Example 323 | 1-[2-(Azetidin-1-yl)-2-o...)
Affinity DataIC50: 41nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent