BDBM437057 (R/S)-6-(4-Fluoro-3-methyl-phenyl)-1-(2-hydroxy-4-methoxy-butyl)-3- methyl-imidazo[4,5-b]pyridin-2-one::US10617676, Example 393::US11207298, Example 393

SMILES COCCC(O)Cn1c2cc(cnc2n(C)c1=O)-c1ccc(F)c(C)c1

InChI Key InChIKey=ILWBWXMIRLGWFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437057   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437057(US10617676, Example 393 | (R/S)-6-(4-Fluoro-3-meth...)
Affinity DataIC50: 486nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437057(US10617676, Example 393 | (R/S)-6-(4-Fluoro-3-meth...)
Affinity DataIC50: 486nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent