BDBM4374 (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid::(2E)-3-(4-hydroxyphenyl)prop-2-enoic acid (8)::CHEMBL66879::p-Coumaric Acid::p-Hydroxycinnamic acid (p-HCA)::p-hydroxycinnamic acid::p-hydroxycinnamic acid (M4)

SMILES: c1cc(ccc1/C=C/C(=O)O)O

InChI Key: InChIKey=NGSWKAQJJWESNS-UHFFFAOYSA-N

Data: 23 KI  15 IC50  2 EC50

PDB links: 103 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 4374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL62 (Baker's yeast)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor beta (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL62 (Baker's yeast)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	7.5	37
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Polyphenol oxidase 2 (White button mushroom)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B10 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL12 (Baker's yeast)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Bovine)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	7.6	25
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Aldo-keto reductase family 1 member B1 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Siderophore-binding protein (Mycobacterium tuberculosis)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		600	-8.48	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 2 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.56E+3	-7.92	n/a	n/a	n/a	n/a	n/a	7.5	25
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Beta-carbonic anhydrase 1 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		3.03E+3	-7.52	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 7 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.96E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		6.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		6.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		7.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		8.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		8.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Mouse)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Mouse)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hydroxycarboxylic acid receptor 2 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		4.41E+5	-4.57	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 2 (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.37E+5	-4.46	n/a	n/a	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor (Human)	BDBM4374 (p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+6	n/a	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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