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BDBM4407 4-Anilidoquinazoline deriv. 23a::6-methyl-N-(2-methylphenyl)quinazolin-4-amine

SMILES: Cc1ccc2ncnc(Nc3ccccc3C)c2c1

InChI Key: InChIKey=MTZMNJDZBLFIAM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4407   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM4407
PNG
(4-Anilidoquinazoline deriv. 23a | 6-methyl-N-(2-me...)
Show SMILES Cc1ccc2ncnc(Nc3ccccc3C)c2c1
Show InChI InChI=1S/C16H15N3/c1-11-7-8-15-13(9-11)16(18-10-17-15)19-14-6-4-3-5-12(14)2/h3-10H,1-2H3,(H,17,18,19)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Hebrew University of Jerusalem



Assay Description
The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.


Bioorg Med Chem 4: 1203-7 (1996)


Article DOI: 10.1021/jm060466d
BindingDB Entry DOI: 10.7270/Q2BC3WR8
More data for this
Ligand-Target Pair