BDBM4421 (2E)-3-(3,4-dihydroxyphenyl)-2-(piperidin-1-ylcarbonyl)prop-2-enenitrile::Tyrphostin deriv. 71

SMILES Oc1ccc(\C=C(/C#N)C(=O)N2CCCCC2)cc1O

InChI Key InChIKey=LNRHMUVQCQDANC-XYOKQWHBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4421   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4421((2E)-3-(3,4-dihydroxyphenyl)-2-(piperidin-1-ylcarb...)
Affinity DataIC50: >1.00E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed