BDBM4468 4-(4-Isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 31::6,7-dimethoxy-4-{[4-(propan-2-yl)phenyl]amino}quinoline-3-carbonitrile

SMILES COc1cc2ncc(C#N)c(Nc3ccc(cc3)C(C)C)c2cc1OC

InChI Key InChIKey=GRSMJKZUNQCQJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4468   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM4468(4-(4-Isopropylphenylamino)-6,7-dimethoxyquinoline-...)
Affinity DataIC50:  229nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM4468(4-(4-Isopropylphenylamino)-6,7-dimethoxyquinoline-...)
Affinity DataIC50:  230nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed