BDBM451802 US10710980, Example 34::US10947218, Example 34

SMILES: Nc1ncc(cc1C(=O)NC12CCC(O)(CC1)CC2)-c1ccc(cc1)[C@@]12C[C@@H]1CN(C2)C1CCOCC1

InChI Key: InChIKey=KPRPFTOLWQQUAV-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 451802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activin receptor type-1 [172-499] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1A [198-525] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499,R206H] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase receptor R3 [166-493] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	323	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 [162-503] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1B (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A [198-525] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499,R206H] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 [166-493] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	323	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 [162-503] (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (Human)	BDBM451802 (US10710980, Example 34 | US10947218, Example 34) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair