BDBM451999 US10710986, Example 139::US11555029, No. 139

SMILES: COc1nc(cnc1CNC[C@@H]1CCC(=O)N1)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CNC[C@@H]2CCC(=O)N2)c(OC)n1

InChI Key: InChIKey=OIIOPWHTJZYKIL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 451999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 [19-238]/protein 1 [25-167] (Human)	BDBM451999 (US10710986, Example 139 | US11555029, No. 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.213	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM451999 (US10710986, Example 139 | US11555029, No. 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.213	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM451999 (US10710986, Example 139 | US11555029, No. 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM451999 (US10710986, Example 139 | US11555029, No. 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM451999 (US10710986, Example 139 | US11555029, No. 139) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair