BDBM452629 7-bromo-5-methyl-3-[[3- [rac-(3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl]-1,2,4- oxadiazol-5-yl]methyl] imidazo[5,1-f][1,2,4] triazin-4-one::US10710994, Example 107

SMILES Cc1nc(Br)n2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c(=O)c12

InChI Key InChIKey=ZCIFHOGRCNHUOK-GXTWGEPZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452629   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452629(7-bromo-5-methyl-3-[[3- [rac-(3R,5R)-5-(4- chlorop...)
Affinity DataIC50:  0.300nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452629(7-bromo-5-methyl-3-[[3- [rac-(3R,5R)-5-(4- chlorop...)
Affinity DataIC50:  0.800nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent