BDBM453551 4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutanoic acid::US10730849, Example 16

SMILES: COc1cc2cc(sc2cc1OC)C(=O)CCC(=O)O

InChI Key: InChIKey=APCLRHPWFCQIMG-UHFFFAOYSA-N

Data: 1 IC50  9 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 453551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.14E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Mouse)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Mouse)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM453551 (4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair