BDBM454378 US10717742, Example Ia-34::US10882866, Example Ia-34

SMILES: Cc1c(ccc2c1nn3c2C[C@H]4[C@@H]3[C@@H]([C@]5(N4CC6CC6)c7ccc(cc7NC5=O)Cl)c8cccc(c8F)Cl)C(=O)O

InChI Key: InChIKey=AMTXDBGKYPDTTA-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 454378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 [23-117] (Human)	BDBM454378 (US10717742, Example Ia-34 | US10882866, Example Ia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [23-117] (Human)	BDBM454378 (US10717742, Example Ia-34 | US10882866, Example Ia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Human)	BDBM454378 (US10717742, Example Ia-34 | US10882866, Example Ia...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair