BDBM4566 4-anilinoquinazoline deriv. 1::CHEMBL91867::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide

SMILES: CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key: InChIKey=BTYYWOYVBXILOJ-UHFFFAOYSA-N

Data: 12 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 4566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	22
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Chicken)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4566 (N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair