BDBM461301 US10774068, Example 107::US10774068, Example 8::US11427560, Example 8

SMILES CCOc1cc2c(cc1NC(=O)CCCN(C)C)c(c(cn2)C#N)Nc3ccc(c(c3)Cl)OCc4ccccn4

InChI Key InChIKey=MIURWHKJMYMLCP-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 461301   

TargetSerine/threonine-protein kinase 4(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase 4(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 550nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase 4(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 550nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 550nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 3(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM461301(US10774068, Example 107 | US10774068, Example 8 | ...)
Affinity DataIC50: 550nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
US Patent