BDBM4619 Anilinoquinazoline deriv. 2::CHEMBL1204360::CHEMBL150581::N-(2-Fluorophenyl)-6,7-dimethoxy-4-quinazolinylamine::N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES: COc1cc2ncnc(Nc3ccccc3F)c2cc1OC

InChI Key: InChIKey=MBQWMGKHDDVEPF-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 4619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	7.4	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	25
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Fibroblast growth factor receptor 1 (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
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Epidermal growth factor receptor (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32.2	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.8	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4619 (N-(2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair