BDBM4621 Anilinoquinazoline deriv. 4::CHEMBL150315::N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES: COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC

InChI Key: InChIKey=YHUIUSRCUKUUQA-UHFFFAOYSA-N

Data: 13 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 4621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.4	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	25
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Fibroblast growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Ephrin type-B receptor 2 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 2 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Human)	BDBM4621 (N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair