BDBM462180 US10766884, Example C02::US11220494, Example C02

SMILES CC(C)n1c(nc2c(F)cc(cc12)-c1nc(N[C@@H]2CCOC[C@H]2O)ncc1Cl)C1CNC1

InChI Key InChIKey=NNNILSWONKWIJC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 462180   

LigandPNGBDBM462180(US10766884, Example C02 | US11220494, Example C02)
Affinity DataKi:  4.10nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462180(US10766884, Example C02 | US11220494, Example C02)
Affinity DataKi:  4.10nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462180(US10766884, Example C02 | US11220494, Example C02)
Affinity DataKi:  89.3nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462180(US10766884, Example C02 | US11220494, Example C02)
Affinity DataKi:  89.3nMAssay Description:CDK6/Cyclin D3: The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent