BDBM4622 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol::Anilinoquinazoline deriv. 5::CHEMBL127907

SMILES: COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)O

InChI Key: InChIKey=BNDYIYYKEIXHNK-UHFFFAOYSA-N

Data: 16 IC50  3 Kd

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 4622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau-tubulin kinase 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
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Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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MO15-related protein kinase Pfmrk (malaria parasite P. falciparum)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tau-tubulin kinase 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
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Ephrin type-B receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Tau-tubulin kinase 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM4622 (CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	25
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