BDBM4629 3-{[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenol::Anilinoquinazoline deriv. 12

SMILES COCCOc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC

InChI Key InChIKey=UXTWDPHPOWZONL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4629   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4629(3-{[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4629(3-{[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50:  7.00E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4629(3-{[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...)
Affinity DataIC50: <5nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed