BDBM46437 US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one

SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)C1NC(=O)NC(=C1c1ccsc1)c1ccccc1

InChI Key InChIKey=CKYLUTWAKNOUEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 46437   

TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
N30 Pharmaceuticals

US Patent
LigandPNGBDBM46437(US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-...)
Affinity DataIC50:  19nMpH: 7.4 T: 2°CAssay Description:Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent