BDBM4659 4-Anilinoquinazoline 6::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-methylpiperazin-1-yl)ethoxy]quinazolin-4-amine

SMILES: COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCN(C)CC1

InChI Key: InChIKey=GSFNVLNOUTVLFC-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Human)	BDBM4659 (N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM4659 (N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	25
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Fibroblast growth factor receptor 1 (Human)	BDBM4659 (N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Epidermal growth factor receptor (Human)	BDBM4659 (N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair