BDBM46726 US8906933, 3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid

SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cccnc1

InChI Key InChIKey=LZWHVDIVHJSYTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 46726   

TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
N30 Pharmaceuticals

US Patent
LigandPNGBDBM46726(US8906933, 3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-...)
Affinity DataIC50:  150nMpH: 7.4 T: 2°CAssay Description:Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent