BDBM469332 (S)-1-(2-(4-(5-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[1,2-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)-1-(4-fluorophenyl)ethanol ::US10807985, Compound 107

SMILES Cn1cc(cn1)-c1cn2ncnc(N3CCN(CC3)c3ncc(cn3)[C@](C)(O)c3ccc(F)cc3)c2c1Cl

InChI Key InChIKey=QNCLKIYNKSIRGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469332   

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM469332((S)-1-(2-(4-(5-chloro-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50: 100nMAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent