BDBM472759 2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US10829492, Example 36

SMILES: NC(=O)c1c(N)nn2ccc(nc12)N1C[C@@H](F)C[C@@H]1c1cc(F)ccc1F

InChI Key: InChIKey=YFTARXQOKASKBW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 472759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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NT-3 growth factor receptor (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor [G667C] (Human)	BDBM472759 (2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
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