BDBM474673 US10849883, Compound 99e

SMILES CC(C)N(CC(=O)NCc1cccc(Cl)c1F)C(=O)Cn1cc(C(C)=O)c2cc(ccc12)C#C[Si](C)(C)C

InChI Key InChIKey=PGRRUSROKBZHLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474673   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474673(US10849883, Compound 99e)
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent