BDBM47622 4-(3-bromophenyl)-6-(2-furanyl)-2-oxo-1H-pyridine-3-carbonitrile::4-(3-bromophenyl)-6-(2-furyl)-2-keto-1H-pyridine-3-carbonitrile::4-(3-bromophenyl)-6-(2-furyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile::4-(3-bromophenyl)-6-(furan-2-yl)-2-oxidanylidene-1H-pyridine-3-carbonitrile::4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine-3-carbonitrile::MLS000690791::SMR000301247::cid_5213229

SMILES Brc1cccc(c1)-c1cc([nH]c(=O)c1C#N)-c1ccco1

InChI Key InChIKey=RFLXOGDEYMPGQY-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 47622   

TargetHuntingtin(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47622(4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine...)
Affinity DataIC50: 5.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetCysteine protease ATG4B(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47622(4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine...)
Affinity DataIC50: 7.76E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetPhospholipase A2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47622(4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine...)
Affinity DataIC50: 1.17E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
LigandPNGBDBM47622(4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine...)
Affinity DataEC50:  4.93E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay