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BDBM4777 4-Anilinopyrido[3,4-d]pyrimidine 3::CHEMBL51659::N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}prop-2-enamide

SMILES: Brc1cccc(Nc2ncnc3cnc(NC(=O)C=C)cc23)c1

InChI Key: InChIKey=OLYVUTGQXNIQQG-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4777
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM4777 (N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.910	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4777 (N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM4777 (N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM4777 (N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair