BDBM478306 2-cyclopropyl-1-{4-[(2-{[6-(5-methoxy-2-methylpyridin-4-yl)-1H-benzimidazol-2-yl]amino}pyridin-4-yl)methyl]piperazin-1-yl}ethanone::US10894784, Example 07.04

SMILES COc1cnc(C)cc1-c1ccc2nc(Nc3cc(CN4CCN(CC4)C(=O)CC4CC4)ccn3)[nH]c2c1

InChI Key InChIKey=KGONWVXABIMELO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478306   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478306(US10894784, Example 07.04 | 2-cyclopropyl-1-{4-[(2...)
Affinity DataIC50: 444nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent