BDBM478631 3,3,3-trifluoro-1-[4-({2-[(6-{6-[(3-methoxypropyl)amino]pyrimidin-4-yl}-1H-benzimidazol-2-yl)amino]pyridin-4-yl}methyl)piperazin-1-yl]propan-1-one::US10894784, Example 90.02

SMILES COCCCNc1cc(ncn1)-c1ccc2nc(Nc3cc(CN4CCN(CC4)C(=O)CC(F)(F)F)ccn3)[nH]c2c1

InChI Key InChIKey=IDNJRWRYUHQXDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478631   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478631(US10894784, Example 90.02 | 3,3,3-trifluoro-1-[4-(...)
Affinity DataIC50: 11nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent