BDBM47902 1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione::1-[(E)-3-phenylprop-2-enyl]indole-2,3-dione::1-[(E)-cinnamyl]isatin::MLS001202142::SMR000565059::cid_2057118

SMILES O=C1N(C\C=C\c2ccccc2)c2ccccc2C1=O

InChI Key InChIKey=OJMNUQNZECRSCJ-RMKNXTFCSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47902   

Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47902(1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione |...)
Affinity DataIC50:  1.12E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47902(1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione |...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47902(1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione |...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47902(1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ALDH2 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47902(1-[(2E)-3-phenylprop-2-enyl]-1H-indole-2,3-dione |...)
Affinity DataIC50:  310nMAssay Description:Inhibition of full length human ALDH3A1 expressed in Escherichia coli BL21 (DE3) using benzaldehyde as substrate preincubated for 2 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed