BDBM48009 8-fluoranylindolo[2,1-b]quinazoline-6,12-dione::8-fluoroindolo[2,1-b]quinazoline-6,12-dione::8-fluoroindolo[2,1-b]quinazoline-6,12-quinone::MLS001216278::SMR000544298::US10669273, Compound 5c::cid_478574

SMILES: Fc1ccc-2c(c1)C(=O)c1nc3ccccc3c(=O)n-21

InChI Key: InChIKey=UXBGZQXHNVNPFT-UHFFFAOYSA-N

Data: 3 KI  14 IC50  1 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 48009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 2,3-dioxygenase (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	937	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 2 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Indoleamine 2,3-dioxygenase 2 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	534	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.68E+4	n/a	n/a	n/a	n/a	n/a
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Tryptophan 2,3-dioxygenase (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein HSP 90-alpha (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
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Sentrin-specific protease 8 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	985	n/a	n/a	n/a	n/a	n/a	n/a
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Sentrin-specific protease 8 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	985	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-9 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptotic protease-activating factor 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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POsterior Segregation (Caenorhabditis elegans)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		336	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM48009 (SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair